> ## Documentation Index
> Fetch the complete documentation index at: https://docs.valyu.ai/llms.txt
> Use this file to discover all available pages before exploring further.

# Healthcare & Biomedical API for AI - PubMed, Clinical Trials, Drug Data

> Search PubMed, clinical trials, ChEMBL, DrugBank, and FDA drug labels through one API. Build AI agents with access to authoritative biomedical and healthcare data.

Search clinical trials, drug information, scientific literature, and pharmaceutical data. Valyu gives you authoritative medical information through a single API.

## What You Can Do

* **Clinical research** - Access trials, study results, and treatment outcomes
* **Drug discovery** - Monitor drug development, interactions, and approvals
* **Biomedical research** - Search PubMed, ArXiv, and academic journals
* **Patient care** - Find treatment guidelines, drug interactions, and clinical evidence
* **Pharma intelligence** - Track pharmaceutical companies and pipeline developments

## Features

<CardGroup cols={2}>
  <Card title="Clinical Trials Database" icon="flask">
    Access ongoing and completed trials from ClinicalTrials.gov with detailed protocols.
  </Card>

  <Card title="Drug Information" icon="pills">
    Drug labels, bioactive molecules, and comprehensive drug databases from DailyMed, ChEMBL, PubChem, and DrugBank.
  </Card>

  <Card title="Scientific Literature" icon="book-medical">
    Millions of biomedical papers from PubMed, ArXiv, and academic journals.
  </Card>

  <Card title="Pharma Intelligence" icon="chart-mixed">
    Pharmaceutical company developments, SEC filings, and competitive intelligence.
  </Card>
</CardGroup>

## Available Datasets

### Clinical Research

| **Dataset**                   | **Content**                                  | **Use Case**                      |
| ----------------------------- | -------------------------------------------- | --------------------------------- |
| `valyu/valyu-clinical-trials` | Clinical trials from ClinicalTrials.gov      | Trial monitoring and enrolment    |
| `valyu/valyu-drug-labels`     | FDA drug labels from DailyMed                | Drug safety and prescribing       |
| `valyu/valyu-chembl`          | Bioactive molecules from ChEMBL              | Drug discovery and screening      |
| `valyu/valyu-pubchem`         | Chemical compounds from PubChem              | Compound data and bioassays       |
| `valyu/valyu-drugbank`        | Comprehensive drug database from DrugBank    | Drug information and research     |
| `valyu/valyu-open-targets`    | Drug target validation from Open Targets     | Target identification             |
| `valyu/valyu-npi-registry`    | US healthcare provider registry              | Provider lookup and verification  |
| `valyu/valyu-who-icd`         | WHO International Classification of Diseases | Disease coding and classification |
| `valyu/valyu-pubmed`          | Biomedical literature from PubMed            | Scientific research               |
| `valyu/valyu-arxiv`           | Pre-print scientific papers                  | Latest research                   |
| `valyu/valyu-biorxiv`         | Life sciences preprints                      | Life sciences research            |
| `valyu/valyu-medrxiv`         | Health and clinical research preprints       | Clinical research preprints       |

### Pharmaceutical Business

| **Dataset**               | **Content**                          | **Use Case**                   |
| ------------------------- | ------------------------------------ | ------------------------------ |
| `valyu/valyu-sec-filings` | Pharmaceutical company SEC documents | Business strategy and pipeline |
| `valyu/valyu-stocks`      | Pharma stock prices and performance  | Market analysis                |
| `valyu/valyu-earnings-US` | Quarterly earnings reports           | Financial performance          |

<Tip>
  Use clinical trials and drug labels for treatment info. Use ChEMBL, PubChem, DrugBank, and Open Targets for drug discovery and target data. Use NPI Registry for provider lookup. Use WHO ICD for disease classification. Use PubMed/ArXiv for research evidence. Use SEC filings for pharmaceutical business intelligence.
</Tip>

## Quick Start

### Basic Search

Let Valyu find the right datasets automatically:

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  response = valyu.search(
      "CAR-T therapy effectiveness in pediatric leukemia latest studies"
  )

  print(response)

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const response = await valyu.search("CAR-T therapy effectiveness in pediatric leukemia latest studies");

  console.log(response);
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "CAR-T therapy effectiveness in pediatric leukemia latest studies"
    }'
  ```
</CodeGroup>

### Clinical Trials

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  response = valyu.search(
      "Phase 3 melanoma immunotherapy trials currently recruiting",
      included_sources=["valyu/valyu-clinical-trials"]
  )

  # Get trial details by NCT ID
  trial_details = valyu.search(
      "clinical trial NCT04916431 detailed protocol"
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const response = await valyu.search(
    "Phase 3 melanoma immunotherapy trials currently recruiting",
    {
      includedSources: ['valyu/valyu-clinical-trials']
    }
  );

  const trialDetails = await valyu.search("clinical trial NCT04916431 detailed protocol");
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "Phase 3 melanoma immunotherapy trials currently recruiting",
      "included_sources": ["valyu/valyu-clinical-trials"]
    }'
  ```
</CodeGroup>

### Drug Information

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # Drug interactions
  response = valyu.search(
      "warfarin drug interactions contraindications bleeding risk",
      included_sources=["valyu/valyu-drug-labels"]
  )

  # Side effects
  side_effects = valyu.search(
      "metformin common side effects dosing adjustments renal impairment"
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const response = await valyu.search(
    "warfarin drug interactions contraindications bleeding risk",
    {
      includedSources: ['valyu/valyu-drug-labels']
    }
  );

  const sideEffects = await valyu.search("metformin common side effects dosing adjustments renal impairment");
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "warfarin drug interactions contraindications bleeding risk",
      "included_sources": ["valyu/valyu-drug-labels"]
    }'
  ```
</CodeGroup>

### Drug Discovery

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # Bioactive molecules
  response = valyu.search(
      "EGFR inhibitors kinase activity IC50 values",
      included_sources=["valyu/valyu-chembl"]
  )

  # Drug targets and mechanisms
  drug_targets = valyu.search(
      "aspirin mechanism target proteins COX inhibition",
      included_sources=["valyu/valyu-drugbank"]
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const response = await valyu.search(
    "EGFR inhibitors kinase activity IC50 values",
    {
      includedSources: ['valyu/valyu-chembl']
    }
  );

  const drugTargets = await valyu.search(
    "aspirin mechanism target proteins COX inhibition",
    {
      includedSources: ['valyu/valyu-drugbank']
    }
  );
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "EGFR inhibitors kinase activity IC50 values",
      "included_sources": ["valyu/valyu-chembl"]
    }'
  ```
</CodeGroup>

### Target Identification

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # Drug targets and disease associations
  response = valyu.search(
      "BRAF target validation melanoma drug discovery",
      included_sources=["valyu/valyu-open-targets"]
  )

  # Target tractability
  targets = valyu.search(
      "kinase targets tractability small molecule",
      included_sources=["valyu/valyu-open-targets"]
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const response = await valyu.search(
    "BRAF target validation melanoma drug discovery",
    {
      includedSources: ['valyu/valyu-open-targets']
    }
  );

  const targets = await valyu.search(
    "kinase targets tractability small molecule",
    {
      includedSources: ['valyu/valyu-open-targets']
    }
  );
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "BRAF target validation melanoma drug discovery",
      "included_sources": ["valyu/valyu-open-targets"]
    }'
  ```
</CodeGroup>

### Provider Lookup

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # Healthcare provider search
  response = valyu.search(
      "cardiologist New York City accepting patients",
      included_sources=["valyu/valyu-npi-registry"]
  )

  # Provider verification
  provider = valyu.search(
      "NPI 1234567890 provider details specialty",
      included_sources=["valyu/valyu-npi-registry"]
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const response = await valyu.search(
    "cardiologist New York City accepting patients",
    {
      includedSources: ['valyu/valyu-npi-registry']
    }
  );

  const provider = await valyu.search(
    "NPI 1234567890 provider details specialty",
    {
      includedSources: ['valyu/valyu-npi-registry']
    }
  );
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "cardiologist New York City accepting patients",
      "included_sources": ["valyu/valyu-npi-registry"]
    }'
  ```
</CodeGroup>

### Disease Classification

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # ICD code lookup
  response = valyu.search(
      "diabetes mellitus type 2 ICD-10 codes",
      included_sources=["valyu/valyu-who-icd"]
  )

  # Disease classification
  classification = valyu.search(
      "acute myocardial infarction classification coding",
      included_sources=["valyu/valyu-who-icd"]
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const response = await valyu.search(
    "diabetes mellitus type 2 ICD-10 codes",
    {
      includedSources: ['valyu/valyu-who-icd']
    }
  );

  const classification = await valyu.search(
    "acute myocardial infarction classification coding",
    {
      includedSources: ['valyu/valyu-who-icd']
    }
  );
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "diabetes mellitus type 2 ICD-10 codes",
      "included_sources": ["valyu/valyu-who-icd"]
    }'
  ```
</CodeGroup>

## Advanced Usage

### Biomedical Literature

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # CRISPR research
  crispr_research = valyu.search(
      "CRISPR-Cas9 off-target effects safety studies 2024",
      included_sources=["valyu/valyu-pubmed", "valyu/valyu-arxiv"],
      max_num_results=10
  )

  # COVID-19 studies
  covid_studies = valyu.search(
      "COVID-19 long-term neurological effects peer-reviewed studies",
      start_date="2023-01-01",
      end_date="2024-12-31"
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const crisprResearch = await valyu.search(
    "CRISPR-Cas9 off-target effects safety studies 2024",
    {
      includedSources: ['valyu/valyu-pubmed', 'valyu/valyu-arxiv'],
      maxNumResults: 10
    }
  );

  const covidStudies = await valyu.search(
    "COVID-19 long-term neurological effects peer-reviewed studies",
    {
      startDate: "2023-01-01",
      endDate: "2024-12-31"
    }
  );
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "CRISPR-Cas9 off-target effects safety studies 2024",
      "included_sources": ["valyu/valyu-pubmed", "valyu/valyu-arxiv"],
      "max_num_results": 10
    }'
  ```
</CodeGroup>

### Pharma Company Analysis

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  pfizer_analysis = valyu.search(
      "Pfizer oncology pipeline clinical trials SEC filings 2024",
      included_sources=[
          "valyu/valyu-sec-filings",
          "valyu/valyu-clinical-trials",
          "valyu/valyu-stocks"
      ]
  )

  pipeline = valyu.search(
      "Moderna mRNA vaccine pipeline development Phase 2 Phase 3 trials"
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const pfizerAnalysis = await valyu.search(
    "Pfizer oncology pipeline clinical trials SEC filings 2024",
    {
      includedSources: [
        'valyu/valyu-sec-filings',
        'valyu/valyu-clinical-trials',
        'valyu/valyu-stocks'
      ]
    }
  );

  const pipeline = await valyu.search("Moderna mRNA vaccine pipeline development Phase 2 Phase 3 trials");
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "Pfizer oncology pipeline clinical trials SEC filings 2024",
      "included_sources": ["valyu/valyu-sec-filings", "valyu/valyu-clinical-trials", "valyu/valyu-stocks"]
    }'
  ```
</CodeGroup>

### Multi-Source Search

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  comprehensive = valyu.search(
      "immunotherapy checkpoint inhibitors melanoma treatment outcomes",
      included_sources=[
          "valyu/valyu-clinical-trials",
          "valyu/valyu-drug-labels",
          "valyu/valyu-pubmed",
          "valyu/valyu-sec-filings"
      ],
      max_num_results=20
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const comprehensive = await valyu.search(
    "immunotherapy checkpoint inhibitors melanoma treatment outcomes",
    {
      includedSources: [
        'valyu/valyu-clinical-trials',
        'valyu/valyu-drug-labels',
        'valyu/valyu-pubmed',
        'valyu/valyu-sec-filings'
      ],
      maxNumResults: 20
    }
  );
  ```

  ```bash cURL theme={null}
  curl -X POST https://api.valyu.ai/v1/search \
    -H "x-api-key: your-valyu-api-key" \
    -H "Content-Type: application/json" \
    -d '{
      "query": "immunotherapy checkpoint inhibitors melanoma treatment outcomes",
      "included_sources": ["valyu/valyu-clinical-trials", "valyu/valyu-drug-labels", "valyu/valyu-pubmed", "valyu/valyu-sec-filings"],
      "max_num_results": 20
    }'
  ```
</CodeGroup>

## Examples

### Clinical Research

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # Treatment comparison
  treatment_comparison = valyu.search(
      "CAR-T versus chemotherapy acute lymphoblastic leukemia outcomes",
      max_num_results=15
  )

  # Treatment guidelines
  guidelines = valyu.search(
      "NCCN guidelines breast cancer HER2 positive treatment 2024",
      included_sources=["valyu/valyu-pubmed"]
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const treatmentComparison = await valyu.search(
    "CAR-T versus chemotherapy acute lymphoblastic leukemia outcomes",
    {
      maxNumResults: 15
    }
  );

  const guidelines = await valyu.search(
    "NCCN guidelines breast cancer HER2 positive treatment 2024",
    {
      includedSources: ['valyu/valyu-pubmed']
    }
  );
  ```
</CodeGroup>

### Drug Safety

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # Interactions
  interactions = valyu.search(
      "apixaban warfarin drug interactions bleeding risk elderly patients",
      included_sources=["valyu/valyu-drug-labels"]
  )

  # Adverse events
  adverse_events = valyu.search(
      "pembrolizumab immune-related adverse events management guidelines"
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const interactions = await valyu.search(
    "apixaban warfarin drug interactions bleeding risk elderly patients",
    {
      includedSources: ['valyu/valyu-drug-labels']
    }
  );

  const adverseEvents = await valyu.search("pembrolizumab immune-related adverse events management guidelines");
  ```
</CodeGroup>

### Biomedical Research

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # Gene therapy
  gene_therapy = valyu.search(
      "AAV gene therapy Duchenne muscular dystrophy clinical outcomes",
      included_sources=["valyu/valyu-pubmed", "valyu/valyu-clinical-trials"]
  )

  # Biomarkers
  biomarkers = valyu.search(
      "liquid biopsy ctDNA early cancer detection sensitivity specificity"
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const geneTherapy = await valyu.search(
    "AAV gene therapy Duchenne muscular dystrophy clinical outcomes",
    {
      includedSources: ['valyu/valyu-pubmed', 'valyu/valyu-clinical-trials']
    }
  );

  const biomarkers = await valyu.search("liquid biopsy ctDNA early cancer detection sensitivity specificity");
  ```
</CodeGroup>

### Pharma Market Intelligence

<CodeGroup>
  ```python Python theme={null}
  from valyu import Valyu

  valyu = Valyu("your-api-key-here")

  # Pipeline analysis
  pipeline_analysis = valyu.search(
      "Roche Genentech oncology pipeline Phase 3 trials FDA approval timeline",
      included_sources=[
          "valyu/valyu-sec-filings",
          "valyu/valyu-clinical-trials"
      ]
  )

  # Market competition
  competition = valyu.search(
      "biosimilar market Humira competition revenue projections 2024-2025"
  )

  ```

  ```javascript TypeScript theme={null}
  import { Valyu } from 'valyu-js';

  const valyu = new Valyu("your-api-key-here");

  const pipelineAnalysis = await valyu.search(
    "Roche Genentech oncology pipeline Phase 3 trials FDA approval timeline",
    {
      includedSources: [
        'valyu/valyu-sec-filings',
        'valyu/valyu-clinical-trials'
      ]
    }
  );

  const competition = await valyu.search("biosimilar market Humira competition revenue projections 2024-2025");
  ```
</CodeGroup>

## Choosing the Right Dataset

<Warning>
  Choose the right dataset for your needs. Clinical trials give protocol details, drug labels provide safety info, ChEMBL, PubChem, DrugBank, and Open Targets offer drug discovery data, NPI Registry provides provider information, WHO ICD offers disease classification, and PubMed offers research evidence.
</Warning>

### Clinical Trials

Use for:

* Finding recruiting trials
* Analysing treatment protocols
* Comparing study designs
* Tracking drug development
* Understanding inclusion/exclusion criteria

```python theme={null}
response = valyu.search(
    "breast cancer HER2 positive recruiting trials Phase 3",
    included_sources=["valyu/valyu-clinical-trials"]
)
```

### Drug Labels

Use for:

* Prescribing information
* Contraindications and warnings
* Drug-drug interactions
* Dosing guidelines
* Adverse reactions

```python theme={null}
response = valyu.search(
    "rituximab infusion reactions premedication protocols",
    included_sources=["valyu/valyu-drug-labels"]
)
```

### ChEMBL

Use for:

* Drug discovery screening
* Bioactive molecule properties
* Target activity data
* IC50 and binding affinity values
* Chemical structure searches

```python theme={null}
response = valyu.search(
    "kinase inhibitors ATP binding site selectivity",
    included_sources=["valyu/valyu-chembl"]
)
```

### PubChem

Use for:

* Chemical compound information
* Molecular structures and properties
* Bioassay data and results
* Compound-target interactions
* Chemical similarity searches

```python theme={null}
response = valyu.search(
    "aspirin molecular structure pharmacological properties",
    included_sources=["valyu/valyu-pubchem"]
)
```

### DrugBank

Use for:

* Drug mechanisms of action
* Pharmacology and pharmacokinetics
* Drug target information
* Metabolic pathways
* Chemical and biological properties

```python theme={null}
response = valyu.search(
    "methotrexate target enzymes mechanism cancer therapy",
    included_sources=["valyu/valyu-drugbank"]
)
```

### Open Targets

Use for:

* Drug target validation
* Disease-target associations
* Target tractability assessment
* Genetic evidence for targets
* Drug discovery prioritization

```python theme={null}
response = valyu.search(
    "EGFR target validation lung cancer genetic evidence",
    included_sources=["valyu/valyu-open-targets"]
)
```

### NPI Registry

Use for:

* Healthcare provider lookup
* NPI number verification
* Provider specialty search
* Practice location details
* Credentialing and verification

```python theme={null}
response = valyu.search(
    "oncologist providers Boston area specialties",
    included_sources=["valyu/valyu-npi-registry"]
)
```

### WHO ICD

Use for:

* Disease code lookup
* ICD-10 and ICD-11 codes
* Medical classification
* Diagnosis coding
* Healthcare billing codes

```python theme={null}
response = valyu.search(
    "chronic kidney disease stage 3 ICD-10 code",
    included_sources=["valyu/valyu-who-icd"]
)
```

### Scientific Literature

Use for:

* Evidence-based medicine
* Latest research findings
* Systematic reviews
* Treatment efficacy studies
* Mechanistic understanding

```python theme={null}
response = valyu.search(
    "checkpoint inhibitor resistance mechanisms melanoma",
    included_sources=["valyu/valyu-pubmed", "valyu/valyu-arxiv"]
)
```

### Pharma Business Data

Use for:

* Pipeline valuations
* R\&D investments
* Competitive landscape
* Market strategy
* M\&A activity

```python theme={null}
response = valyu.search(
    "Pfizer R&D spending oncology portfolio strategy",
    included_sources=["valyu/valyu-sec-filings", "valyu/valyu-earnings-US"]
)
```

## Best Practices

<Tip>
  Start with descriptive medical queries and let Valyu find relevant datasets.
  Use `included_sources` only when you need specific data types.
</Tip>

### Effective Queries

| **Query Type**          | **Example**                                               | **Why It Works**                    |
| ----------------------- | --------------------------------------------------------- | ----------------------------------- |
| **Clinical Trials**     | "Phase 3 NSCLC immunotherapy trials currently recruiting" | Specific phase, condition, status   |
| **Drug Information**    | "metformin contraindications renal dosing adjustments"    | Specific drug with clinical context |
| **Research Literature** | "CAR-T therapy cytokine release syndrome management 2024" | Current year, specific condition    |
| **Pharma Analysis**     | "Moderna pipeline mRNA vaccines Phase 2 Phase 3"          | Company with development stages     |

### Source Selection

**Clinical Evidence**:

```python theme={null}
included_sources = [
    "valyu/valyu-pubmed",
    "valyu/valyu-clinical-trials",
    "valyu/valyu-drug-labels"
]
```

**Drug Development**:

```python theme={null}
included_sources = [
    "valyu/valyu-clinical-trials",
    "valyu/valyu-sec-filings",
    "valyu/valyu-pubmed"
]
```

**Pharmaceutical Business**:

```python theme={null}
included_sources = [
    "valyu/valyu-sec-filings",
    "valyu/valyu-stocks",
    "valyu/valyu-earnings-US"
]
```

### Tips

1. **Use medical terminology**: Standard terms, drug names, and disease classifications
2. **Be specific about trials**: Include phase, NCT numbers, or recruitment status
3. **Add time context**: Publication years or date ranges for current research
4. **Focus on conditions**: Specify diseases, patient populations, or treatment types

## Limitations

* **Data currency**: Clinical trial data may have 24-48 hour update delays
* **Regional coverage**: Currently focused on US trials and FDA-approved drugs
* **Access levels**: Some academic content may require subscriptions
* **Medical disclaimer**: Information is for research purposes only—not a substitute for professional medical advice