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Search clinical trials, drug information, scientific literature, and pharmaceutical data. Valyu gives you authoritative medical information through a single API.

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What You Can Do

  • Clinical research - Access trials, study results, and treatment outcomes
  • Drug discovery - Monitor drug development, interactions, and approvals
  • Biomedical research - Search PubMed, ArXiv, and academic journals
  • Patient care - Find treatment guidelines, drug interactions, and clinical evidence
  • Pharma intelligence - Track pharmaceutical companies and pipeline developments

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Features

Clinical Trials Database

Access ongoing and completed trials from ClinicalTrials.gov with detailed protocols.

Drug Information

Drug labels, bioactive molecules, and comprehensive drug databases from DailyMed, ChEMBL, PubChem, and DrugBank.

Scientific Literature

Millions of biomedical papers from PubMed, ArXiv, and academic journals.

Pharma Intelligence

Pharmaceutical company developments, SEC filings, and competitive intelligence.

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Available Datasets

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Clinical Research

DatasetContentUse Case
valyu/valyu-clinical-trialsClinical trials from ClinicalTrials.govTrial monitoring and enrolment
valyu/valyu-drug-labelsFDA drug labels from DailyMedDrug safety and prescribing
valyu/valyu-chemblBioactive molecules from ChEMBLDrug discovery and screening
valyu/valyu-pubchemChemical compounds from PubChemCompound data and bioassays
valyu/valyu-drugbankComprehensive drug database from DrugBankDrug information and research
valyu/valyu-open-targetsDrug target validation from Open TargetsTarget identification
valyu/valyu-npi-registryUS healthcare provider registryProvider lookup and verification
valyu/valyu-who-icdWHO International Classification of DiseasesDisease coding and classification
valyu/valyu-pubmedBiomedical literature from PubMedScientific research
valyu/valyu-arxivPre-print scientific papersLatest research
valyu/valyu-biorxivLife sciences preprintsLife sciences research
valyu/valyu-medrxivHealth and clinical research preprintsClinical research preprints

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Pharmaceutical Business

DatasetContentUse Case
valyu/valyu-sec-filingsPharmaceutical company SEC documentsBusiness strategy and pipeline
valyu/valyu-stocksPharma stock prices and performanceMarket analysis
valyu/valyu-earnings-USQuarterly earnings reportsFinancial performance
Use clinical trials and drug labels for treatment info. Use ChEMBL, PubChem, DrugBank, and Open Targets for drug discovery and target data. Use NPI Registry for provider lookup. Use WHO ICD for disease classification. Use PubMed/ArXiv for research evidence. Use SEC filings for pharmaceutical business intelligence.

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Quick Start

Let Valyu find the right datasets automatically: 
from valyu import Valyu

valyu = Valyu("your-api-key-here")

response = valyu.search(
    "CAR-T therapy effectiveness in pediatric leukemia latest studies"
)

print(response)

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Clinical Trials

from valyu import Valyu

valyu = Valyu("your-api-key-here")

response = valyu.search(
    "Phase 3 melanoma immunotherapy trials currently recruiting",
    included_sources=["valyu/valyu-clinical-trials"]
)

# Get trial details by NCT ID
trial_details = valyu.search(
    "clinical trial NCT04916431 detailed protocol"
)

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Drug Information

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# Drug interactions
response = valyu.search(
    "warfarin drug interactions contraindications bleeding risk",
    included_sources=["valyu/valyu-drug-labels"]
)

# Side effects
side_effects = valyu.search(
    "metformin common side effects dosing adjustments renal impairment"
)

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Drug Discovery

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# Bioactive molecules
response = valyu.search(
    "EGFR inhibitors kinase activity IC50 values",
    included_sources=["valyu/valyu-chembl"]
)

# Drug targets and mechanisms
drug_targets = valyu.search(
    "aspirin mechanism target proteins COX inhibition",
    included_sources=["valyu/valyu-drugbank"]
)

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Target Identification

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# Drug targets and disease associations
response = valyu.search(
    "BRAF target validation melanoma drug discovery",
    included_sources=["valyu/valyu-open-targets"]
)

# Target tractability
targets = valyu.search(
    "kinase targets tractability small molecule",
    included_sources=["valyu/valyu-open-targets"]
)

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Provider Lookup

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# Healthcare provider search
response = valyu.search(
    "cardiologist New York City accepting patients",
    included_sources=["valyu/valyu-npi-registry"]
)

# Provider verification
provider = valyu.search(
    "NPI 1234567890 provider details specialty",
    included_sources=["valyu/valyu-npi-registry"]
)

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Disease Classification

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# ICD code lookup
response = valyu.search(
    "diabetes mellitus type 2 ICD-10 codes",
    included_sources=["valyu/valyu-who-icd"]
)

# Disease classification
classification = valyu.search(
    "acute myocardial infarction classification coding",
    included_sources=["valyu/valyu-who-icd"]
)

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Advanced Usage

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Biomedical Literature

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# CRISPR research
crispr_research = valyu.search(
    "CRISPR-Cas9 off-target effects safety studies 2024",
    included_sources=["valyu/valyu-pubmed", "valyu/valyu-arxiv"],
    max_num_results=10
)

# COVID-19 studies
covid_studies = valyu.search(
    "COVID-19 long-term neurological effects peer-reviewed studies",
    start_date="2023-01-01",
    end_date="2024-12-31"
)

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Pharma Company Analysis

from valyu import Valyu

valyu = Valyu("your-api-key-here")

pfizer_analysis = valyu.search(
    "Pfizer oncology pipeline clinical trials SEC filings 2024",
    included_sources=[
        "valyu/valyu-sec-filings",
        "valyu/valyu-clinical-trials",
        "valyu/valyu-stocks"
    ]
)

pipeline = valyu.search(
    "Moderna mRNA vaccine pipeline development Phase 2 Phase 3 trials"
)


from valyu import Valyu

valyu = Valyu("your-api-key-here")

comprehensive = valyu.search(
    "immunotherapy checkpoint inhibitors melanoma treatment outcomes",
    included_sources=[
        "valyu/valyu-clinical-trials",
        "valyu/valyu-drug-labels",
        "valyu/valyu-pubmed",
        "valyu/valyu-sec-filings"
    ],
    max_num_results=20
)

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Examples

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Clinical Research

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# Treatment comparison
treatment_comparison = valyu.search(
    "CAR-T versus chemotherapy acute lymphoblastic leukemia outcomes",
    max_num_results=15
)

# Treatment guidelines
guidelines = valyu.search(
    "NCCN guidelines breast cancer HER2 positive treatment 2024",
    included_sources=["valyu/valyu-pubmed"]
)

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Drug Safety

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# Interactions
interactions = valyu.search(
    "apixaban warfarin drug interactions bleeding risk elderly patients",
    included_sources=["valyu/valyu-drug-labels"]
)

# Adverse events
adverse_events = valyu.search(
    "pembrolizumab immune-related adverse events management guidelines"
)

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Biomedical Research

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# Gene therapy
gene_therapy = valyu.search(
    "AAV gene therapy Duchenne muscular dystrophy clinical outcomes",
    included_sources=["valyu/valyu-pubmed", "valyu/valyu-clinical-trials"]
)

# Biomarkers
biomarkers = valyu.search(
    "liquid biopsy ctDNA early cancer detection sensitivity specificity"
)

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Pharma Market Intelligence

from valyu import Valyu

valyu = Valyu("your-api-key-here")

# Pipeline analysis
pipeline_analysis = valyu.search(
    "Roche Genentech oncology pipeline Phase 3 trials FDA approval timeline",
    included_sources=[
        "valyu/valyu-sec-filings",
        "valyu/valyu-clinical-trials"
    ]
)

# Market competition
competition = valyu.search(
    "biosimilar market Humira competition revenue projections 2024-2025"
)

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Choosing the Right Dataset

Choose the right dataset for your needs. Clinical trials give protocol details, drug labels provide safety info, ChEMBL, PubChem, DrugBank, and Open Targets offer drug discovery data, NPI Registry provides provider information, WHO ICD offers disease classification, and PubMed offers research evidence.

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Clinical Trials

Use for:
  • Finding recruiting trials
  • Analysing treatment protocols
  • Comparing study designs
  • Tracking drug development
  • Understanding inclusion/exclusion criteria
response = valyu.search(
    "breast cancer HER2 positive recruiting trials Phase 3",
    included_sources=["valyu/valyu-clinical-trials"]
)

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Drug Labels

Use for:
  • Prescribing information
  • Contraindications and warnings
  • Drug-drug interactions
  • Dosing guidelines
  • Adverse reactions
response = valyu.search(
    "rituximab infusion reactions premedication protocols",
    included_sources=["valyu/valyu-drug-labels"]
)

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ChEMBL

Use for:
  • Drug discovery screening
  • Bioactive molecule properties
  • Target activity data
  • IC50 and binding affinity values
  • Chemical structure searches
response = valyu.search(
    "kinase inhibitors ATP binding site selectivity",
    included_sources=["valyu/valyu-chembl"]
)

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PubChem

Use for:
  • Chemical compound information
  • Molecular structures and properties
  • Bioassay data and results
  • Compound-target interactions
  • Chemical similarity searches
response = valyu.search(
    "aspirin molecular structure pharmacological properties",
    included_sources=["valyu/valyu-pubchem"]
)

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DrugBank

Use for:
  • Drug mechanisms of action
  • Pharmacology and pharmacokinetics
  • Drug target information
  • Metabolic pathways
  • Chemical and biological properties
response = valyu.search(
    "methotrexate target enzymes mechanism cancer therapy",
    included_sources=["valyu/valyu-drugbank"]
)

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Open Targets

Use for:
  • Drug target validation
  • Disease-target associations
  • Target tractability assessment
  • Genetic evidence for targets
  • Drug discovery prioritization
response = valyu.search(
    "EGFR target validation lung cancer genetic evidence",
    included_sources=["valyu/valyu-open-targets"]
)

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NPI Registry

Use for:
  • Healthcare provider lookup
  • NPI number verification
  • Provider specialty search
  • Practice location details
  • Credentialing and verification
response = valyu.search(
    "oncologist providers Boston area specialties",
    included_sources=["valyu/valyu-npi-registry"]
)

​
WHO ICD

Use for:
  • Disease code lookup
  • ICD-10 and ICD-11 codes
  • Medical classification
  • Diagnosis coding
  • Healthcare billing codes
response = valyu.search(
    "chronic kidney disease stage 3 ICD-10 code",
    included_sources=["valyu/valyu-who-icd"]
)

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Scientific Literature

Use for:
  • Evidence-based medicine
  • Latest research findings
  • Systematic reviews
  • Treatment efficacy studies
  • Mechanistic understanding
response = valyu.search(
    "checkpoint inhibitor resistance mechanisms melanoma",
    included_sources=["valyu/valyu-pubmed", "valyu/valyu-arxiv"]
)

​
Pharma Business Data

Use for:
  • Pipeline valuations
  • R&D investments
  • Competitive landscape
  • Market strategy
  • M&A activity
response = valyu.search(
    "Pfizer R&D spending oncology portfolio strategy",
    included_sources=["valyu/valyu-sec-filings", "valyu/valyu-earnings-US"]
)

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Best Practices

Start with descriptive medical queries and let Valyu find relevant datasets. Use included_sources only when you need specific data types.

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Effective Queries

Query TypeExampleWhy It Works
Clinical Trials”Phase 3 NSCLC immunotherapy trials currently recruiting”Specific phase, condition, status
Drug Information”metformin contraindications renal dosing adjustments”Specific drug with clinical context
Research Literature”CAR-T therapy cytokine release syndrome management 2024”Current year, specific condition
Pharma Analysis”Moderna pipeline mRNA vaccines Phase 2 Phase 3”Company with development stages

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Source Selection

Clinical Evidence: 
included_sources = [
    "valyu/valyu-pubmed",
    "valyu/valyu-clinical-trials",
    "valyu/valyu-drug-labels"
]
Drug Development: 
included_sources = [
    "valyu/valyu-clinical-trials",
    "valyu/valyu-sec-filings",
    "valyu/valyu-pubmed"
]
Pharmaceutical Business: 
included_sources = [
    "valyu/valyu-sec-filings",
    "valyu/valyu-stocks",
    "valyu/valyu-earnings-US"
]

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Tips

  1. Use medical terminology: Standard terms, drug names, and disease classifications
  2. Be specific about trials: Include phase, NCT numbers, or recruitment status
  3. Add time context: Publication years or date ranges for current research
  4. Focus on conditions: Specify diseases, patient populations, or treatment types

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Limitations

  • Data currency: Clinical trial data may have 24-48 hour update delays
  • Regional coverage: Currently focused on US trials and FDA-approved drugs
  • Access levels: Some academic content may require subscriptions
  • Medical disclaimer: Information is for research purposes only—not a substitute for professional medical advice